New Publication: Zebrafish and microplastics

We published new research on the uptake and effect of microplastics on zebrafish embryos and larvae. The main take home messages:

  • Zebrafish larvae exposed to PS particles had minimal biodistribution.
  • Internalized particles caused an immune response by activating the complement system.
  • Enriched toxicity pathways for lipid metabolism and oxidative stress were detected.
  • Our results can be used to develop Adverse Outcome Pathways for microplastics.

Figure_6

Figure showing uptake of polystyrene particles by neutrophils using fluorescence microscopy.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: