We published new research on the uptake and effect of microplastics on zebrafish embryos and larvae. The main take home messages:
- Internalized particles caused an immune response by activating the complement system.
- Enriched toxicity pathways for lipid metabolism and oxidative stress were detected.
- Our results can be used to develop Adverse Outcome Pathways for microplastics.
Figure showing uptake of polystyrene particles by neutrophils using fluorescence microscopy.