New Publication: Zebrafish and microplastics

We published new research on the uptake and effect of microplastics on zebrafish embryos and larvae. The main take home messages:

  • Zebrafish larvae exposed to PS particles had minimal biodistribution.
  • Internalized particles caused an immune response by activating the complement system.
  • Enriched toxicity pathways for lipid metabolism and oxidative stress were detected.
  • Our results can be used to develop Adverse Outcome Pathways for microplastics.


Figure showing uptake of polystyrene particles by neutrophils using fluorescence microscopy.


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